Title: Analysis of the biological functions of H-and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin
نویسندگان
چکیده
We describe the use of small interfering RNAs (siRNAs) to downregulate Hand L-ferritin levels in HeLa cells. They repressed Hand L-ferritin expression to about 20-25% of the background level, both in stable and transient transfections. HeLa cells transfected with Hand L
منابع مشابه
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin.
We describe the use of small interfering RNAs (siRNAs) to down-regulate H- and L-ferritin levels in HeLa cells. siRNAs repressed H- and L-ferritin expression to about 20% to 25% of the background level in both stable and transient transfections. HeLa cells transfected with H- and L-ferritin cDNAs were analyzed in parallel to compare the effects of ferritin up- and down-regulation. We found that...
متن کاملL-ferritin transfection with siRNAs and cDNAs: evidence for a proliferative role of Analysis of the biologic functions of H- and L-ferritins in HeLa cells
http://bloodjournal.hematologylibrary.org/content/103/6/2377.full.html Updated information and services can be found at: (1174 articles) Red Cells Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online a...
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